& amp; nbsp & amp; nbsp & amp; nbsp & amp; nbsp human vocal cord tissue was successfully cultured in laboratory
& nbsp & amp; nbsp & amp; nbsp & amp; nbsp & amp; nbsp is expected to make patients vocalize again
& nbsp & amp; nbsp & amp; nbsp & amp; nbsp & amp; nbsp & amp; nbsp science and technology daily, Beijing, September 24 (Reporter Zhang Menglan), according to a medical research published by British magazine《自然通讯》on the 24th, a three-dimensional model of human vocal cord tissue (i.e. mucosa) was developed by the American team in the laboratory. The model can be used to study drugs and therapies related to vocal cord diseases or lesions.
& Am; nbsp& nbsp& nbsp& nbsp& nbsp& nbsp vocal cord vibration function requires it to be flexible enough, vibration characteristics of hundreds of times per second also requires it to be strong enough, so human vocal cord is a very "delicate" system, which has been extremely difficult to replicate. However, the vocal cords are susceptible to chronic inflammation, mainly caused by environmental damage, including cigarettes, allergens or infections. Because extracting cell samples from healthy vocal cords can cause irreversible damage, it has been a long-standing problem for scientists to study vocal cords diseases and repair strategies.
& On the basis of previous studies on mice, human induced pluripotent stem cells (hiPSC) were extracted from vocal cord epithelial cells by using amp; nbsp & amp; nbsp & amp; nbsp & amp; nbsp & amp; nbsp. This time, Susan Sabat, a scientist at the University of Wisconsin, Madison, and his colleagues. Studies have shown that hiPSC-derived vocal cord tissue is genetically and morphologically similar to natural human vocal cord mucosa.